ᱟᱱᱴᱤᱵᱚᱰᱤ: ᱨᱮᱱᱟᱜ ᱫᱚᱦᱲᱟᱭᱮᱱ ᱛᱟᱞᱟᱨᱮᱭᱟᱜ ᱯᱷᱟᱨᱟᱠ ᱠᱚ
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Fagu Baskey (ᱨᱚᱲ | ᱮᱱᱮᱢ) No edit summary |
Fagu Baskey (ᱨᱚᱲ | ᱮᱱᱮᱢ) No edit summary |
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ᱫᱷᱟᱹᱲ ᱒:
'''ᱟᱱᱴᱤᱵᱚᱰᱤ''' ᱵᱟᱝᱢᱟ '''ᱮ ᱵᱤ''' ([[ᱤᱝᱞᱤᱥ ᱯᱟᱹᱨᱥᱤ]]ᱛᱮ An '''antibody''' ('''Ab''')), ᱟᱨᱦᱚᱸ '''ᱤᱢᱭᱩᱱᱚᱜᱽᱞᱚᱵᱤᱱ''' ᱵᱟᱝᱢᱟ '''ᱟᱭ ᱡᱤ''' (ᱤᱝᱞᱤᱥ ᱯᱟᱹᱨᱥᱤ ᱛᱮ) '''immunoglobulin''' ('''Ig''')),<ref name=Rhoades>{{cite book | vauthors = Rhoades RA, Pflanzer RG | title = Human Physiology | edition = 5th | publisher = Thomson Learning | year = 2002 | page = [https://archive.org/details/humanphysiologyw00rodn/page/584 584] | isbn = 978-0-534-42174-8 | url = https://archive.org/details/humanphysiologyw00rodn/page/584 }}</ref> ᱫᱚ ᱢᱤᱫ ᱢᱟᱨᱟᱝ ᱣᱟᱭ ᱟᱠᱟᱨ ᱨᱮᱭᱟᱜ ᱯᱨᱚᱴᱤᱱ ᱡᱟᱦᱟᱸ ᱫᱚ ᱯᱞᱟᱥᱢᱟ ᱡᱤᱵᱚᱠᱚᱥᱚ ᱛᱮ ᱵᱮᱱᱟᱜ-ᱟ ᱟᱨ ᱤᱢᱭᱩᱱ ᱥᱤᱥᱴᱚᱢ ([[:en:immune system|immune system]]) ᱫᱟᱨᱟᱭ ᱛᱮ ᱟᱡᱟᱨ ᱵᱮᱱᱟᱣ ᱵᱷᱩᱣᱟᱹᱬᱤ ([[:en:Viral disease|viruses]]) ᱟᱨᱵᱟᱝ ᱡᱤᱭᱟᱹᱬᱤ ᱮ ᱜᱚᱡ ᱠᱚᱣᱟ ᱾
ᱯᱟᱛᱷᱚᱡᱮᱱ ᱨᱮᱭᱟᱜ ᱢᱤᱫ ᱚᱛᱩᱞᱟᱹᱱᱤᱭᱟᱹ ᱢᱚᱞᱤᱠᱩᱞ ᱛᱮᱡ ᱟᱱᱴᱤᱵᱚᱰᱤ ᱪᱤᱱᱦᱟᱹᱣ ᱫᱟᱲᱮᱭᱟᱜ-ᱟ ᱡᱟᱦᱟᱸ ᱫᱚ ᱟᱱᱴᱤᱡᱮᱱ ᱵᱚ ᱢᱮᱛᱟᱜ ᱠᱟᱱᱟ ᱾ ᱱᱚᱣᱟ ᱫᱚ ᱯᱷᱨᱟᱜᱽᱢᱮᱱᱴ ᱟᱱᱴᱤᱡᱮᱱ ᱵᱟᱭᱤᱱᱰᱤᱝ ᱵᱷᱟᱨᱤᱭᱮᱵᱩᱞ ([[:en:fragment antigen-binding|fragment antigen-binding]] (Fab)) ᱴᱷᱟᱶ ᱨᱮ ᱛᱟᱦᱮᱸᱱᱟᱭ ᱾ <ref name=Janeway5>{{cite book | first = Charles | last = Janeway | name-list-format = vanc | title = Immunobiology | edition = 5th | publisher = Garland Publishing | year = 2001 | url = https://archive.org/details/immunobiology00char | isbn = 978-0-8153-3642-6 }}</ref><ref name="pmid8450761">{{cite journal | vauthors = Litman GW, Rast JP, Shamblott MJ, Haire RN, Hulst M, Roess W, Litman RT, Hinds-Frey KR, Zilch A, Amemiya CT | title = Phylogenetic diversification of immunoglobulin genes and the antibody repertoire | journal = Molecular Biology and Evolution | volume = 10 | issue = 1 | pages = 60–72 | date = January 1993 | pmid = 8450761 | doi = 10.1093/oxfordjournals.molbev.a040000 }}</ref>
ଏହି ବନ୍ଧନ ପ୍ରଣାଳୀ ବ୍ୟବହାର କରି ଆଣ୍ଟିବଡ ଏକ ଅଣୁଜୀବ ବା ସଂକ୍ରମିତ ଜୀବକୋଷକୁ ଟ୍ୟାଗ କରିଦେବା ଫଳରେ ଇମ୍ମ୍ୟୁନ ସିସ୍ଟମର ଅନ୍ୟାନ୍ୟ ଅଂଶ ଆକ୍ରମଣ କରନ୍ତି ଓ ବଞ୍ଚିରହିବାକୁ ଆବଶ୍ୟକ ଏହି ଟାରଗେଟକୁ ନିଉଟ୍ରାଲାଇଜ କରିଦିଅନ୍ତି । ଆଣ୍ଟିଜେନ ଅନୁସାରେ ଏହି ବନ୍ଧନ ଯୋଗୁ ଜୈବିକ କ୍ରିୟା ବାଧାପ୍ରାପ୍ତ ହୁଏ ବା ବାହ୍ୟ ପଦାର୍ଥ ନଷ୍ଟ ହୋଇଯାଏ । "Y"ର ବେସରେ ଥିବା ଫ୍ରାଗମେଣ୍ଟ କ୍ରିସ୍ଟାଲାଇଜେବ୍ଲ ସ୍ଥାନ ଇମ୍ମ୍ୟୁନ ସିସ୍ଟମର ଅନ୍ୟାନ୍ୟ ଅଂଶ ସହିତ ସଂଯୋଗ ସ୍ଥାପନ କରିପାରେ ଓ ଏହି ସ୍ଥାନରେ ଗୋଟେ ସଂରକ୍ଷିତ ଗ୍ଲାଇକୋସିଲାସନ ସ୍ଥାନରେ ପ୍ରତିକ୍ରିୟା ହୁଏ । <ref name = "immune_glycan">{{cite journal | vauthors = Maverakis E, Kim K, Shimoda M, Gershwin ME, Patel F, Wilken R, Raychaudhuri S, Ruhaak LR, Lebrilla CB | title = Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review | journal = Journal of Autoimmunity | volume = 57 | issue = 6 | pages = 1–13 | date = February 2015 | pmid = 25578468 | pmc = 4340844 | doi = 10.1016/j.jaut.2014.12.002 }}</ref> ହ୍ୟୁମୋରାଲ ଇମ୍ମ୍ୟୁନ ସିସ୍ଟମର ([[:en:humoral immune system|humoral immune system]]) ମୁଖ୍ୟ କାମ ହେଉଛି ଆଣ୍ଟିବଡି ପ୍ରସ୍ତୁତ କରିବା ।<ref name=Pier>{{cite book | vauthors = Pier GB, Lyczak JB, Wetzler LM | title = Immunology, Infection, and Immunity | publisher = ASM Press| year = 2004 | isbn = 978-1-55581-246-1}}</ref> | |||